Keywords: پیازولو [3،4-d] پیریمیدین; Unexpected reaction; Pyrazolo[3,4-d]pyrimidine; Tetrazole; Cycloaddition;
مقالات ISI پیازولو [3،4-d] پیریمیدین (ترجمه نشده)
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Synthesis of 4,6-disubstituted pyrazolo[3,4-d]pyrimidine analogues: Cyclin-dependent kinase 2 (CDK2) inhibition, molecular docking and anticancer evaluation
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Cyclin-dependent kinase inhibitor; Anti-proliferative activity; Molecular docking; GLIDE;
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment
Keywords: پیازولو [3،4-d] پیریمیدین; Neuroblastoma; c-Src; Pyrazolo[3,4-d]pyrimidine;
Synthesis, anticancer evaluation, and molecular docking studies of some novel 4,6-disubstituted pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 (CDK2) inhibitors
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Cyclin dependent kinase inhibitor; Anti-proliferative activity; Molecular docking; GLIDE;
Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents
Keywords: پیازولو [3،4-d] پیریمیدین; KLRPLYVCPQRLRB-PJQLUOCWSA-N; TVKDNILWGVYQAU-UHFFFAOYSA-N; BPOQQDJRWDOIEB-UHFFFAOYSA-N; PMZCIEIUZYAOGL-UHFFFAOYSA-N; WCIAWDONFWQAGP-UHFFFAOYSA-N; JKKQWVVDGMTXPR-OMCISZLKSA-N; ORFLBOXAUYGODB-GIDUJCDVSA-N; JENMSLPZSGMTJB-REZTVBANSA-N; AWRYWUXZPWEGMZ-REZTVBAN
Ionic liquid 1-butyl-3-methylimidazolium bromide: A green reaction media for the efficient synthesis of 3-methyl-1,4-diphenyl-1,4,5,7-tetrahydro-pyrazolo[3,4-d]pyrimidine-6-ones/thiones using phthalimide-N-sulfonic acid as catalyst
Keywords: پیازولو [3،4-d] پیریمیدین; 1-Butyl-3-methylimidazolium bromide ([Bmim][Br]); Phthalimide-N-sulfonic acid (PISA); 1-Phenyl-3-methyl-1H-pyrazole-5(4H)-one; Pyrazolo[3,4-d]pyrimidine;
New advances in synthesis and clinical aspects of pyrazolo[3,4-d]pyrimidine scaffolds
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Anti-inflammatory; Anticancer agents; Antimicrobial;
Synthesis and structure-activity relationship study of pyrazolo[3,4-d]pyrimidines as tyrosine kinase RET inhibitors
Keywords: پیازولو [3،4-d] پیریمیدین; Tyrosine kinase RET; Pyrazolo[3,4-d]pyrimidine; Anticancer; Cell proliferation; Structure-activity relationship;
Evaluation and structure-activity relationship analysis of a new series of 4-imino-5H-pyrazolo[3,4-d]pyrimidin-5-amines as potential antibacterial agents
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Hydrazide; New efficient synthesis; Antibacterial activity; Computational study; Quantitative structure-activity relationship;
Novel pyrazolo[3,4-d]pyrimidine with 4-(1H-benzimidazol-2-yl)-phenylamine as broad spectrum anticancer agents: Synthesis, cell based assay, topoisomerase inhibition, DNA intercalation and bovine serum albumin studies
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Benzimidazole; Antitumor activity; ct-DNA; Bovine serum albumin;
Pyrazolo[3,4-d]pyrimidine based scaffold derivatives targeting kinases as anticancer agents
Keywords: پیازولو [3،4-d] پیریمیدین; Protein kinase; Bioisostere; Pyrazolo[3,4-d]pyrimidine; Synthetic strategy; SAR
Design, synthesis and antitumor activity of novel pyrazolo[3,4-d]pyrimidine derivatives as EGFR-TK inhibitors
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Schiff bases; Antitumor; EGFR tyrosine kinase;
Theoretical explorations on the molecular structure and IR frequencies of 3-phenyl-1-tosyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine in view of experimental results
Keywords: پیازولو [3،4-d] پیریمیدین; GAUSSIAN03; Pyrazolo[3,4-d]pyrimidine; Molecular structure; MEP; HOMO-LUMO; Vibrational assignments;
A facile and novel synthesis of N2-, C6-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Carboxylate derivatives; Adenosine receptor antagonists; Homology modeling; Molecular docking; Structure-affinity relationshiphA3AR, human A3 adenosine receptor; SAR, structure-activity relationship; PTP, pyrazolo[4,3-e]1,2,4-tr
Discovery of simplified N2-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: Efficient synthetic approaches, biological evaluations and molecular docking studies
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Adenosine receptor antagonist; Homology modeling; Molecular docking; Structure affinity relationship;
Medicinal attributes of pyrazolo[3,4-d]pyrimidines: A review
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Activities; SAR; IC50;
Synthesis of novel pyrazolo[3,4-d]pyrimidine derivatives as potential anti-breast cancer agents
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Antitumor activity; MCF7;
Gas-phase conformational and intramolecular Ï-Ï interaction studies on some pyrazolo[3,4-d]pyrimidine derivatives
Keywords: پیازولو [3،4-d] پیریمیدین; Conformational stabilities; Pyrazolo[3,4-d]pyrimidine; DFT-D; M06-2X; Potential energy surface scan; GAUSSIAN 09;
Synthesis and in vitro cytotoxic activity of novel pyrazolo[3,4-d]pyrimidines and related pyrazole hydrazones toward breast adenocarcinoma MCF-7 cell line
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Pyrazole; Cytotoxic activity; Oxidative stress;
Molecular iodine promoted synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as potential antibacterial agents
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Antibacterial agents; Iodine; Heterocyclization
Synthesis and 'double click' density functionalization of 8-aza-7-deazaguanine DNA bearing branched side chains with terminal triple bonds
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; Modified bases; Cycloaddition; Click reaction; DNA; Nucleosides; Oligonucleotides;
Development of multitargeted inhibitors of both the insulin-like growth factor receptor (IGF-IR) and members of the epidermal growth factor family of receptor tyrosine kinases
Keywords: پیازولو [3،4-d] پیریمیدین; Insulin-like growth factor receptor (IGF-IR); EGFR; ErbB-2; Kinase; Inhibitor; Pyrazolo[3,4-d]pyrimidine
Studies on arene interactions in flexible pyrazolo[3,4-d]pyrimidine core based symmetrical 'propylene/Leonard linker' models: X-ray crystallographic evidence for disappearance of intramolecular stacking due to presence of chloro- or cyano-groups in place
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; X-ray crystallography; Ï-Ï interactions; Clâ¦Ï interactions;
Synthesis and antiviral evaluation of some new pyrazole and fused pyrazolopyrimidine derivatives
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazole; Pyrazolo[3,4-d]pyrimidine; S- and N-nucleosides; Antiviral activity
Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines
Keywords: پیازولو [3،4-d] پیریمیدین; Adenosine A2A receptor antagonists; Parkinson’s disease; Pyrazolo[3,4-d]pyrimidine; Pyrrolo[2,3-d]pyrimidine; Purine
Unusual effect of bulky isopropyl group on robustness of the U-motif in pyrazolo[3,4-d]pyrimidine core based 'Leonard linker' compounds in comparison to methyl/ethyl group: A1H NMR and X-ray crystallographic study
Keywords: پیازولو [3،4-d] پیریمیدین; Pyrazolo[3,4-d]pyrimidine; X-ray crystallography; Arene interactions; U-motif;
Pyrazolo[3,4-d]pyrimidines as potent inhibitors of the insulin-like growth factor receptor (IGF-IR)
Keywords: پیازولو [3،4-d] پیریمیدین; Insulin-like growth factor receptor (IGF-IR); Kinase; Inhibitor; Pyrazolo[3,4-d]pyrimidine